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Secnidazole

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Secnidazole
Secnidazole.svg
Clinical data
Trade names Solosec
Other names PM 185184, RP 14539
AHFS/Drugs.com International Drug Names
License data
Routes of
administration
Oral
ATC code
Legal status
Legal status
Identifiers
  • 1-(2-Methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.020.123
Chemical and physical data
Formula C7H11N3O3
Molar mass 185.183 g·mol−1
3D model (JSmol)
  • [O-] [N+](=O)c1cnc(n1CC(O)C)C
  • InChI=1S/C7H11N3O3/c1-5(11)4-9-6(2)8-3-7(9)10(12)13/h3,5,11H,4H2,1-2H3 checkY
  • Key:KPQZUUQMTUIKBP-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Secnidazole (trade names Flagentyl, Sindose, Secnil, Solosec) is a nitroimidazole anti-infective. Effectiveness in the treatment of dientamoebiasis has been reported. It has also been tested against Atopobium vaginae.

In the United States, secnidazole is FDA approved for the treatment of bacterial vaginosis and trichomoniasis in adult women.

Further reading

  • Gillis JC, Wiseman LR (April 1996). "Secnidazole. A review of its antimicrobial activity, pharmacokinetic properties and therapeutic use in the management of protozoal infections and bacterial vaginosis". Drugs. 51 (4): 621–38. doi:10.2165/00003495-199651040-00007. PMID 8706597.

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