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Selective receptor modulator
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Selective receptor modulator

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Selective receptor modulator
Drug class
Tamoxifen2DACS.svg
Tamoxifen, a SERM and a widely used drug in the treatment of breast cancer.
Class identifiers
Synonyms SRM
Use Various
Biological target Steroid hormone receptor
Chemical class Steroidal; Nonsteroidal
In Wikidata

In the field of pharmacology, a selective receptor modulator or SRM is a type of drug that has different effects in different tissues. A SRM may behave as an agonist in some tissues while as an antagonist in others. Hence selective receptor modulators are sometimes referred to as tissue selective drugs or mixed agonists / antagonists. This tissue selective behavior is in contrast to many other drugs that behave either as agonists or antagonists regardless of the tissue in question.

Note that selective estrogen receptor modulator (SERM) is the only class of these drugs currently on the market in the US.

Classes

Classes of selective receptor modulators include:

See also



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