Serotonin–norepinephrine releasing agent
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Further information: serotonin releasing agent and norepinephrine releasing agent
MBDB, an SNRA.
Norfenfluramine, an SNRA.
A serotonin–norepinephrine releasing agent (SNRA) is a type of drug which induces the release of serotonin and norepinephrine (and epinephrine) in the body and/or brain.
Only a few SNRAs are known, examples of which include norfenfluramine and MBDB. Fenfluramine/phentermine (Fen-Phen), a combination formulation of fenfluramine, a serotonin releasing agent, and phentermine, a norepinephrine releasing agent, is a functional SNRA that was formerly used as an appetite suppressant for the treatment of obesity.
A closely related type of drug is a serotonin–norepinephrine reuptake inhibitor (SNRI).
See also
- Monoamine releasing agent
- Serotonin releasing agent
- Norepinephrine releasing agent
- Serotonin–dopamine releasing agent
- Serotonin–norepinephrine–dopamine releasing agent
| TAAR1 |
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| TAAR2 |
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| TAAR5 |
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† References for all endogenous human TAAR1 ligands are provided at List of trace amines
‡ References for synthetic TAAR1 agonists can be found at TAAR1 or in the associated compound articles. For TAAR2 and TAAR5 agonists and inverse agonists, see TAAR for references.
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