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SR-17018

Другие языки:

SR-17018

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SR-17018
Identifiers

IUPAC name 5,6-dichloro-3-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-1H-benzimidazol-2-one
CAS Number	2134602-45-0^Y
PubChem CID	130431397
ChemSpider	67886365
UNII	2M8P7UAW4W
ChEMBL	ChEMBL4452384
PDB ligand	WH9 (PDBe, RCSB PDB)
Chemical and physical data
Formula	C₁₉H₁₈Cl₃N₃O
Molar mass	410.72 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1CN(CCC1N2C3=CC(=C(C=C3NC2=O)Cl)Cl)CC4=CC=C(C=C4)Cl
InChI InChI=1S/C19H18Cl3N3O/c20-13-3-1-12(2-4-13)11-24-7-5-14(6-8-24)25-18-10-16(22)15(21)9-17(18)23-19(25)26/h1-4,9-10,14H,5-8,11H2,(H,23,26) Key:LAGUDYUGRSQDKS-UHFFFAOYSA-N

SR-17018 is a drug which acts as a biased agonist at the μ-opioid receptor, selective for activation of the G-protein signalling pathway over β-arrestin 2 recruitment. In animal studies it produces analgesic effects but with less respiratory depression and development of tolerance than conventional opioids.

See also