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Respiratory system drug stubs
Suplatast tosilate
Другие языки:

    Suplatast tosilate

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    Suplatast tosilate
    Suplatast tosilate.png
    Clinical data
    AHFS/Drugs.com International Drug Names
    Routes of
    administration    		 Oral
    ATC code
    • none
    Legal status
    Legal status
    • In general: ℞ (Prescription only)
    Identifiers
    • (3-{[4-(3-ethoxy-2-hydroxypropoxy)phenyl]amino}-3-oxopropyl)(dimethyl)sulfonium 4-methylbenzenesulfonate
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    KEGG
    ChEMBL
    CompTox Dashboard (EPA)
    ECHA InfoCard 100.220.132
    Chemical and physical data
    Formula C23H33NO7S2
    Molar mass 499.64 g·mol−1
    3D model (JSmol)
    • CCOCC(COC1=CC=C(C=C1)NC(=O)CC[S+](C)C)O.CC1=CC=C(C=C1)S(=O)(=O)[O-]
    • InChI=1S/C16H25NO4S.C7H8O3S/c1-4-20-11-14(18)12-21-15-7-5-13(6-8-15)17-16(19)9-10-22(2)3;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,14,18H,4,9-12H2,1-3H3;2-5H,1H3,(H,8,9,10) ☒N
    • Key:RYVJQEZJUFRANT-UHFFFAOYSA-N ☒N
     ☒NcheckY (what is this?)  (verify)

    Suplatast tosilate (INN) is a Th2 cytokine inhibitor which is used as an antihistamine. It has been suggested and applied in the treatment of Kimura's disease a few times.

    Further reading

    • Taniguchi H, Togawa M, Ohwada K, et al. (December 1996). "Suplatast tosilate, a new type of antiallergic agent, prevents the expression of airway hyperresponsiveness in guinea pigs". European Journal of Pharmacology. 318 (2–3): 447–54. doi:10.1016/S0014-2999(96)00810-2. PMID 9016937.
    • Sano Y (December 1996). "[Anti-inflammatory drugs for the treatment of bronchial hyperresponsiveness]". Nihon Kyōbu Shikkan Gakkai Zasshi (in Japanese). 34 Suppl: 48–53. PMID 9216184.



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