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Table of volume of distribution for drugs
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    Table of volume of distribution for drugs

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    This is a table of volume of distribution (Vd) for various medication. For comparison, those with a Vd L/kg body weight of less than 0.2 are mainly distributed in blood plasma, 0.2-0.7 mostly in the extracellular fluid and those with more than 0.7 are distributed throughout total body water.

    Medication Vd L/kg body weight
    heparin 0.05-0.1
    insulin 0.05-0.1
    warfarin 0.1-0.2
    sulfamethoxazole 0.1-0.2
    glibenclamide 0.1-0.2
    atenolol 0.1-0.2
    NXY-059 0.1-0.2
    tubocurarine 0.2-0.4
    theophylline 0.4-0.7
    ethanol 0.7-0.9
    neostigmine 0.7-0.9
    phenytoin 0.7-0.9
    methotrexate 1-2
    indometacin 1-2
    paracetamol 1-2
    diazepam 1-2
    lidocaine 1-2
    glyceryl trinitrate 2-5
    morphine 2-5
    propranolol 2-5
    digoxin 2-5
    chlorpromazine 2-5
    nortriptyline 2-5
    chloroquine 200

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