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Abandoned drugs
Tampramine
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Tampramine

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Tampramine
Tampramine.svg
Clinical data
Routes of
administration		 Oral
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • N,N-Dimethyl-3-(6-phenylpyrido[2,3-b][1,4]benzodiazepin-11-yl)propan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C23H24N4
Molar mass 356.473 g·mol−1
3D model (JSmol)
  • CN(C)CCCN1c2ccccc2C(=Nc3c1nccc3)c4ccccc4

Tampramine (AHR-9,377) is a tricyclic antidepressant (TCA) which was developed in the 1980s but was never marketed. Despite being a TCA, it acts as a selective norepinephrine reuptake inhibitor and has negligible affinity for adrenergic, histaminergic, and muscarinic receptors. It was found to be effective in the forced swim test (FST) model of depression in animal studies but is not known to have ever been trialed in humans.

See also


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