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Antiinfective agent stubs
Tilorone
Другие языки:

Tilorone

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Tilorone
Tilorone.svg
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration		 By mouth (tablets)
ATC code
Pharmacokinetic data
Bioavailability 60%
Protein binding ~80%
Metabolism Nil
Elimination half-life 48 hours
Excretion Feces (70%), urine (9%)
Identifiers
  • 2,7-Bis(2-diethylaminoethoxy)fluoren-9-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C25H34N2O3
Molar mass 410.558 g·mol−1
3D model (JSmol)
  • CCN(CC)CCOc1ccc-2c(c1)C(=O)c3c2ccc(c3)OCCN(CC)CC
  • InChI=1S/C25H34N2O3/c1-5-26(6-2)13-15-29-19-9-11-21-22-12-10-20(30-16-14-27(7-3)8-4)18-24(22)25(28)23(21)17-19/h9-12,17-18H,5-8,13-16H2,1-4H3 ☒N
  • Key:MPMFCABZENCRHV-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Tilorone (trade names Amixin, Lavomax and others) is the first recognized synthetic, small molecular weight compound that is an orally active interferon inducer. It is used as an antiviral drug in some countries which do not require double-blind placebo-controlled studies, including Russia. It is effective against Ebola virus in mice.

Pharmacology

Tilorone activates the production of interferon.


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