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Human drug metabolites
Tizoxanide
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Tizoxanide

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Tizoxanide
Tizoxanide.svg
Names
Preferred IUPAC name
2-Hydroxy-N-(5-nitro-1,3-thiazol-2-yl)benzamide
Other names
Desacetyl-nitazoxanide
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.263.225
PubChem CID
UNII
  • InChI=1S/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15) checkY
    Key: FDTZUTSGGSRHQF-UHFFFAOYSA-N checkY
  • InChI=1/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15)
    Key: FDTZUTSGGSRHQF-UHFFFAOYAR
  • O=C(Nc1ncc(s1)[N+]([O-])=O)c2ccccc2O
Properties
C10H7N3O4S
Molar mass 265.25 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Tizoxanide, also known as desacetyl-nitazoxanide, is a thiazolide and an antiparasitic agent that occurs as a metabolite of nitazoxanide in humans through hydrolysis. Tizoxanide may undergo further metabolism via conjugation into tizoxanide glucuronide.


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