Topical tac
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TAC stands for tetracaine, adrenaline, and cocaine, it was introduced by Pryor et al. in 1980. TAC is a topical anesthetic solution for local anesthesia and is recommended for use on pediatric patients.
Due to drug diversion concerns surrounding the use of cocaine in medicine, along with concern regarding toxicity and expense, the cocaine was replaced with lidocaine and a new anesthetic was created - lidocaine, epinephrine, and tetracaine (LET).
External links
- Tipton GA, DeWitt GW, Eisenstein SJ (November 1989). "Topical TAC (tetracaine, adrenaline, cocaine) solution for local anesthesia in children: prescribing inconsistency and acute toxicity". Southern Medical Journal. 82 (11): 1344–6. doi:10.1097/00007611-198911000-00004. PMID 2814620.
- US patent 5942543, Ernst, Amy A., "Topical anesthetic comprising lidocaine, adrenaline, and tetracaine, and its method of use", issued August 24, 1999