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Ophthalmic drug administration
Tropicamide/phenylephrine
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    Tropicamide/phenylephrine

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    Tropicamide/phenylephrine
    Combination of
    Tropicamide Anticholinergic
    Phenylephrine Alpha-1 adrenergic receptor agonist
    Clinical data
    Trade names Mydcombi
    Routes of
    administration    		 Topical, ophthalmic
    ATC code
    Legal status
    Legal status

    Tropicamide/phenylephrine, sold under the brand name Mydcombi is a fixed dose combination of tropicamide and phenylephrine used to dilate the eyes (mydriasis). It contains, tropicamide, an anticholinergic, and phenylephrine, as the hydrochloride, an alpha-1 adrenergic receptor agonist. It is sprayed into the eyes.

    It was approved for medical use in the United States in May 2023.

    Medical uses

    Tropicamide/phenylephrine is used for the short-term dilation of the pupils.

    External links

    • Clinical trial number NCT03751631 for "Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation (MIST-1)" at ClinicalTrials.gov
    • Clinical trial number NCT03751098 for "Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation (MIST-2)" at ClinicalTrials.gov



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