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Twin anemia-polycythemia sequence
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    Twin anemia-polycythemia sequence

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    Twin anemia-polycythemia sequence
    TAPS legs twins.jpg
    Twin anemia-polycythemia sequence is a monochorionic twin condition characterized by a large intertwin hemoglobin difference.
    Specialty Obstetrics

    Twin anemia-polycythemia sequence (TAPS) is a form of chronic inter-twin transfusion. It is distinguished from classic twin-to-twin transfusion syndrome by differing red blood cell counts between the fetuses, a relative lack of symptoms and a lack of oligohydramnios or polyhydramnios among the fetuses.

    Monochorionic twin pregnancy complication

    Diagnosis and staging

    Diagnosis by Doppler ultrasound measurement of the Middle Cerebral Artery—Peak Systolic Velocity (MCA-PSV)

    Different stages of TAPS are identified using the criteria as shown in the following tables.

    Postnatal classification

    Postnatal stage Intertwin hemoglobin difference (g/dL)
    Stage 1 >8.0 g/dL
    Stage 2 >11.0 g/dL
    Stage 3 >14.0 g/dL
    Stage 4 >17.0 g/dL
    Stage 5 >20.0 g/dL

    Treatment

    The use of the so-called Solomon technique or dichorionization in fetoscopic laser therapy for twin-to-twin transfusion syndrome is proven to be beneficial in preventing post-laser TAPS. With this technique, not only all anastomoses are coagulated (closed) but also a line is drawn between those in order to coagulate anastomoses that might not (yet) be visible during fetoscopy. It should be stressed that the success of such a technique is highly dependent on the specific situation. For example, when one of the fetuses obstructs the view on the vascular equator (the part of the placenta where the anastomoses need to be coagulated), complete dichorionization by the Solomon technique might not be possible.

    Perinatal outcome

    See also

    External links



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