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UK-414,495
Другие языки:

    UK-414,495

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    UK-414,495
    UK-414,495.svg
    Identifiers
    • (2R)-2-({1-[(5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl]cyclopentyl}methyl)pentanoic acid
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    ChEMBL
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C16H25N3O3S
    Molar mass 339.45 g·mol−1
    3D model (JSmol)
    • CCC[C@H](CC1(CCCC1)C(=O)NC2=NN=C(S2)CC)C(=O)O
    • InChI=1S/C16H25N3O3S/c1-3-7-11(13(20)21)10-16(8-5-6-9-16)14(22)17-15-19-18-12(4-2)23-15/h11H,3-10H2,1-2H3,(H,20,21)(H,17,19,22)/t11-/m1/s1 ☒N
    • Key:FWXXCSISWQQOGS-LLVKDONJSA-N ☒N
     ☒NcheckY (what is this?)  (verify)

    UK-414,495 is a drug developed by Pfizer for the treatment of female sexual arousal disorder. UK-414,495 acts as a potent, selective inhibitor of the enzyme neutral endopeptidase, which normally serves to break down the neuropeptide VIP. The consequent increase in VIP activity alters blood flow to the genital region leading to increased lubrication and muscle relaxation.

    See also



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