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Pharmacology stubs
VGX-1027
Другие языки:

VGX-1027

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VGX-1027
VGX-1027 structure.png
Identifiers
  • 2-(3-phenyl-4,5-dihydro-1,2-oxazol-5-yl)acetic acid
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C11H11NO3
Molar mass 205.213 g·mol−1
3D model (JSmol)
  • C1C(ON=C1C2=CC=CC=C2)CC(=O)O
  • InChI=1S/C11H11NO3/c13-11(14)7-9-6-10(12-15-9)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,14)
  • Key:MUFJHYRCIHHATF-UHFFFAOYSA-N

VGX-1027 (GIT-27) is a drug which acts as an immunomodulator. It acts by blocking downstream signalling of the Toll-like receptors TLR2, TLR4 and TLR6, and thereby reducing production of various cytokines, including interleukins and TNF-α. In animal studies it has antiinflammatory effects and has been investigated for conditions such as arthritis and lung inflammation.


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