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Antibiotic
Yaequinolone J1
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    Yaequinolone J1

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    Yaequinolone J1
    Yaequinolone J1.png
    Names
    IUPAC name
    (2S,9R,10R)-10-Hydroxy-9-methoxy-10-(4-methoxyphenyl)-2-methyl-2-(4-methyl-3-penten-1-yl)-2,7,9,10-tetrahydro-8H-pyrano[2,3-f]quinolin-8-one
    Identifiers
    3D model (JSmol)
    ChemSpider
    PubChem CID
    • InChI=1S/C27H31NO5/c1-17(2)7-6-15-26(3)16-14-18-8-13-21-22(23(18)33-26)27(30,24(32-5)25(29)28-21)19-9-11-20(31-4)12-10-19/h7-14,16,24,30H,6,15H2,1-5H3,(H,28,29)/t24-,26-,27+/m0/s1
      Key: CPWPNTRWIIAFEG-DOEKTCAHSA-N
    • O=C4Nc2c(c1O[C@@](/C=C\c1cc2)(C)CC\C=C(/C)C)[C@](O)(c3ccc(OC)cc3)[C@H]4OC
    Properties
    C27H31NO5
    Molar mass 449.547 g·mol−1
    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

    Yaequinolone J1 is an antibiotic made by Penicillium.

    Total syntheses of yaequinolone J1

    An asymmetric total synthesis of yaequinolone J1 has been published in 2018 by V. Vece, S. Jakkepally and S. Hanessian. In 2020, a five-step synthesis of yaequinolone J1 was reported.



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