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Withdrawn drugs
Zoxazolamine
Другие языки:

Zoxazolamine

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Zoxazolamine
Zoxazolamine.svg
Clinical data
Other names McN-485
Routes of
administration		 Oral
Identifiers
  • 5-Chloro-1,3-benzoxazol-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
Formula C7H5ClN2O
Molar mass 168.58 g·mol−1
3D model (JSmol)
  • C1=CC2=C(C=C1Cl)N=C(O2)N
  • InChI=InChI=1S/C7H5ClN2O/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3H,(H2,9,10)
  • Key:YGCODSQDUUUKIV-UHFFFAOYSA-N

Zoxazolamine (INN, USAN, BAN) (brand name Contrazole, Deflexol, Flexin, Miazol, Uri-Boi, Zoxamine, Zoxine) is a muscle relaxant that is no longer marketed. It was synthesized in 1953 and introduced clinically in 1955 but was withdrawn due to hepatotoxicity. One of its active metabolites, chlorzoxazone, was found to show less toxicity, and was subsequently marketed in place of zoxazolamine. These drugs activate IKCa channels.




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