Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
Psychedelic tryptamines
4-Fluoro-5-methoxy-DMT
Другие языки:

    4-Fluoro-5-methoxy-DMT

    Подписчиков: 0, рейтинг: 0
    4-Fluoro-5-methoxy-DMT
    4-Fluoro-5-methoxy-N,N-dimethyltryptamine.svg
    Identifiers
    • 4-Fluoro-5-Methoxy-N,N-dimethyltryptamine
    CAS Number
    PubChem CID
    ChemSpider
    Chemical and physical data
    Formula C13H17FN2O
    Molar mass 236.290 g·mol−1
    3D model (JSmol)
    • CN(C)CCC1=CNC2=C1C(=C(C=C2)OC)F
    • InChI=1S/C13H17FN2O/c1-16(2)7-6-9-8-15-10-4-5-11(17-3)13(14)12(9)10/h4-5,8,15H,6-7H2,1-3H3
    • Key:CTEKFOKTEGQYLO-UHFFFAOYSA-N
      (verify)

    4-Fluoro-5-Methoxy-N,N-dimethyltryptamine (4-F-5-MeO-DMT) was first described by David E. Nichols team in 2000. It is a potent 5-HT1A agonist. Substitution with the 4-fluorine markedly increased 5-HT1A selectivity over 5-HT2A/2C receptors with potency greater than that of the 5-HT1A agonist 8-OH-DPAT.

    The analog compound with the N,N-dialkyl substituents constrained into a pyrrolidine ring, is a slightly stronger agonist for the 5-HT1A receptor and retains the selectivity over the 5-HT2A/2C receptors.

    See also


    Новое сообщение