Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
SB-649,915
Другие языки:

SB-649,915

Подписчиков: 0, рейтинг: 0
SB-649,915
SB-649,915 structure.png
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • 6-[(1-[3-(2-methylquinolin-5-yl)oxypropyl]piperidin-4-yl)methyl]-4H-1,4-benzoxazin-3-one
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
Chemical and physical data
Formula C26H29N3O3
Molar mass 431.536 g·mol−1
3D model (JSmol)
  • O=C4COc1ccc(cc1N4)CC(CC5)CCN5CCOc(cccc2n3)c2ccc3C
  • InChI=1S/C26H29N3O3/c1-18-5-7-21-22(27-18)3-2-4-24(21)31-14-13-29-11-9-19(10-12-29)15-20-6-8-25-23(16-20)28-26(30)17-32-25/h2-8,16,19H,9-15,17H2,1H3,(H,28,30) ☒N
  • Key:PJSUYRBCBFPCQW-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

SB-649,915 is a serotonin reuptake inhibitor and 5-HT1A and 5-HT1B receptor antagonist which is being investigated for its antidepressant effects. Relative to the selective serotonin reuptake inhibitors (SSRIs), SB-649,915 has a faster onset of action and may also have greater clinical efficacy as well. This can be attributed to blockade of 5-HT1A and 5-HT1Bautoreceptors which inhibit serotonin release.

See also


Новое сообщение