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Monoamine oxidase inhibitor
5-Fluoro-AMT
Другие языки:

    5-Fluoro-AMT

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    5-Fluoro-AMT
    5-fluoro-alpha-methyltryptamine.svg
    5-Fluoro-α-methyltryptamine.png
    Identifiers
    • 1-(5-fluoro-1H-indol-3-yl)propan-2-amine
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    ChEMBL
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C11H13FN2
    Molar mass 192.237 g·mol−1
    3D model (JSmol)
    • Fc1cc2c(cc1)[nH]cc2CC(N)C
    • InChI=1S/C11H13FN2/c1-7(13)4-8-6-14-11-3-2-9(12)5-10(8)11/h2-3,5-7,14H,4,13H2,1H3 checkY
    • Key:CTGFDWBZMCPVED-UHFFFAOYSA-N checkY
     ☒NcheckY (what is this?)  (verify)

    5-Fluoro-α-methyltryptamine (5-Fluoro-αMT, 5F-AMT), also known as PAL-544, is a putative stimulant, entactogen, and psychedelic tryptamine derivative related to α-methyltryptamine (αMT). It has been found to act as a well-balanced serotonin-norepinephrine-dopamine releasing agent, a 5-HT2A receptor agonist, and a potent and specific MAO-A inhibitor. which suggests that 5-fluoro-αMT could be an active psychedelic in humans, although it is not known to have been tested in humans and could be dangerous due to its strong inhibition of MAO-A.

    See also

    Further reading

    • Nakagawasai O, Arai Y, Satoh SE, Satoh N, Neda M, Hozumi M, et al. (January 2004). "Monoamine oxidase and head-twitch response in mice. Mechanisms of alpha-methylated substrate derivatives". Neurotoxicology. 25 (1–2): 223–32. doi:10.1016/S0161-813X(03)00101-3. PMID 14697897.



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