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Antihypertensive
Acetryptine
Другие языки:

    Acetryptine

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    Acetryptine
    Acetryptine.svg
    Clinical data
    Other names W-2965-A; 5-Acetyltryptamine; 5-Acetyl-3-(2-aminoethyl)indole;
    Identifiers
    • 1-[3-(2-Aminoethyl)-1H-indol-5-yl]ethanone
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    ChEMBL
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C12H14N2O
    Molar mass 202.257 g·mol−1
    3D model (JSmol)
    • CC(=O)C1=CC2=C(C=C1)NC=C2CCN
    • InChI=1S/C12H14N2O/c1-8(15)9-2-3-12-11(6-9)10(4-5-13)7-14-12/h2-3,6-7,14H,4-5,13H2,1H3
    • Key:RAUGYAOLAMRLLZ-UHFFFAOYSA-N

    Acetryptine (INN) (developmental code name W-2965-A), also known as 5-acetyltryptamine (5-AT), is a drug described as an antihypertensive agent which was never marketed. Structurally, acetryptine is a substituted tryptamine, and is closely related to other substituted tryptamines like serotonin (5-hydroxytryptamine). It was developed in the early 1960s. The binding of acetryptine to serotonin receptors does not seem to have been well-investigated, although it was assessed at the 5-HT1A and 5-HT1D receptors and found to bind to them with high affinity. The drug may also act as a monoamine oxidase inhibitor (MAOI); specifically, as an inhibitor of MAO-A.

    See also



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