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Alprenolol

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Alprenolol
Alprenolol2.svg
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral
ATC code
Pharmacokinetic data
Protein binding 80% - 90%
Elimination half-life 2-3 hours → 4-OH-alprenolol
Identifiers
  • (RS)-1-(2-allylphenoxy)-3-(isopropylamino)propan-2-ol
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.033.750
Chemical and physical data
Formula C15H23NO2
Molar mass 249.354 g·mol−1
3D model (JSmol)
  • O(c1ccccc1C\C=C)CC(O)CNC(C)C
  • InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3 checkY
  • Key:PAZJSJFMUHDSTF-UHFFFAOYSA-N checkY
  (verify)

Alprenolol, or alfeprol, alpheprol, and alprenololum (Gubernal, Regletin, Yobir, Apllobal, Aptine, Aptol Duriles), is a non-selective beta blocker as well as a 5-HT1A and 5-HT1B receptor antagonist, used in the treatment of angina pectoris. It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically.


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