Aprobarbital

Aprobarbital

Clinical data
Other names	aprobarbitone, Oramon, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid
AHFS/Drugs.com	International Drug Names
ATC code	N05CA05 (WHO)
Legal status
Legal status	CA: Schedule IV
Identifiers
IUPAC name 5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
CAS Number	77-02-1 Y
PubChem CID	6464
DrugBank	DB01352 Y
ChemSpider	6221 Y
UNII	Q0YKG9L6RF
KEGG	D00698 Y
ChEBI	CHEBI:2791 Y
ChEMBL	ChEMBL7863 Y
CompTox Dashboard (EPA)	DTXSID8022616
ECHA InfoCard	100.000.908
Chemical and physical data
Formula	C10H14N2O3
Molar mass	210.233 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C1NC(=O)NC(=O)C1(C(C)C)C\C=C
InChI InChI=1S/C10H14N2O3/c1-4-5-10(6(2)3)7(13)11-9(15)12-8(10)14/h4,6H,1,5H2,2-3H3,(H2,11,12,13,14,15) Y Key:UORJNBVJVRLXMQ-UHFFFAOYSA-N Y
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Aprobarbital (or aprobarbitone), sold as Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia. Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.

See also

• Alphenal