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Bucolome
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Clinical data | |
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Other names | Bucolome, Paramidine |
AHFS/Drugs.com | International Drug Names |
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CAS Number | |
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CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.011.515 |
Chemical and physical data | |
Formula | C14H22N2O3 |
Molar mass | 266.341 g·mol−1 |
3D model (JSmol) | |
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Bucolome (Paramidine) is a barbiturate derivative. Unlike most barbiturates it does not have any significant sedative or hypnotic effects, but instead acts as an analgesic and antiinflammatory. It also acts as a CYP2C9 inhibitor and reduces the metabolism of several commonly used drugs, which makes it useful for potentiating or extending the duration of action of those drugs, or reducing the production of unwanted metabolites.
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acetic acid derivatives and related substances |
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propionic acid derivatives (profens) |
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n-arylanthranilic acids (fenamates) |
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COX-2 inhibitors (coxibs) |
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other | |
NSAID combinations |
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Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use. | |