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Bucolome
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Bucolome

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Bucolome
Bucolome.svg
Clinical data
Other names Bucolome, Paramidine
AHFS/Drugs.com International Drug Names
ATC code
  • none
Identifiers
  • 5-butyl-1-cyclohexyl-1,3-diazinane-2,4,6-trione
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.011.515
Chemical and physical data
Formula C14H22N2O3
Molar mass 266.341 g·mol−1
3D model (JSmol)
  • CCCCC1C(=O)NC(=O)N(C1=O)C2CCCCC2
  • InChI=1S/C14H22N2O3/c1-2-3-9-11-12(17)15-14(19)16(13(11)18)10-7-5-4-6-8-10/h10-11H,2-9H2,1H3,(H,15,17,19) checkY
  • Key:DVEQCIBLXRSYPH-UHFFFAOYSA-N checkY
  (verify)

Bucolome (Paramidine) is a barbiturate derivative. Unlike most barbiturates it does not have any significant sedative or hypnotic effects, but instead acts as an analgesic and antiinflammatory. It also acts as a CYP2C9 inhibitor and reduces the metabolism of several commonly used drugs, which makes it useful for potentiating or extending the duration of action of those drugs, or reducing the production of unwanted metabolites.


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