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Antipsychotic
Fananserin
Другие языки:

    Fananserin

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    Fananserin
    Fananserin.svg
    Clinical data
    Other names Fananserin
    ATC code
    • none
    Identifiers
    • 2-(3-(4-(p-Fluorophenyl)-1-piperazinyl)propyl)-2H-naphth(1,8-cd)isothiazole 1,1-dioxide
    CAS Number
    PubChem CID
    IUPHAR/BPS
    ChemSpider
    UNII
    KEGG
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C23H24FN3O2S
    Molar mass 425.52 g·mol−1
    3D model (JSmol)
    • C1CN(CCN1CCCN2C3=CC=CC4=C3C(=CC=C4)S2(=O)=O)C5=CC=C(C=C5)F
    • InChI=1S/C23H24FN3O2S/c24-19-8-10-20(11-9-19)26-16-14-25(15-17-26)12-3-13-27-21-6-1-4-18-5-2-7-22(23(18)21)30(27,28)29/h1-2,4-11H,3,12-17H2 ☒N
    • Key:VGIGHGMPMUCLIQ-UHFFFAOYSA-N ☒N
     ☒NcheckY (what is this?)  (verify)

    Fananserin (RP-62203) is a drug which acts as a potent antagonist at both the 5HT2A receptor, and the Dopamine D4 receptor, but without blocking other dopamine receptors such as D2. It has sedative and antipsychotic effects, and has been researched for the treatment of schizophrenia, although efficacy was less than expected and results were disappointing.


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