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Fluoroestradiol F-18
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Clinical data | |
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Trade names | Cerianna |
Other names | [18F]16α-Fluoroestradiol; [18F]16α-Fluoroestra-1,3,5(10)-triene-3,17β-diol |
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Routes of administration |
Intravenous injection |
Drug class | Estrogen; Diagnostic radiopharmaceutical |
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Pharmacokinetic data | |
Metabolism | Liver |
Excretion | Gallbladder and kidney |
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Chemical and physical data | |
Formula | C18H23[18F]O2 |
Molar mass | 289.37 |
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Fluoroestradiol F-18, also known as [18F]16α-fluoroestradiol and sold under the brand name Cerianna, is a radioactive diagnostic agent indicated for use with positron emission tomography (PET) imaging. It is an analog of estrogen and is used to detect estrogen receptor-positive breast cancer lesions.
Chemistry
Chemically, fluoroestradiol F-18 is [18F]16α-fluoro-3,17β-diol-estratriene-1,3,5(10).
History
Fluoroestradiol F-18 was approved for medical use in the United States in May 2020.
See also
External links
- "Fluoroestradiol F-18". Drug Information Portal. U.S. National Library of Medicine.
- "Fluoroestradiol F-18". NCI Thesaurus. 4 May 2020.
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