Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
Antidepressant
Pivagabine
Другие языки:

Pivagabine

Подписчиков: 0, рейтинг: 0
Pivagabine
Seletal formula of pivagabine with some implicit hydrogens shown
Names
Preferred IUPAC name
4-(2,2-Dimethylpropanamido)butanoic acid
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.067.287
EC Number
  • 274-038-3
KEGG
MeSH N-trimethylacetyl-4-aminobutyric+acid
PubChem CID
UNII
  • InChI=1S/C9H17NO3/c1-9(2,3)8(13)10-6-4-5-7(11)12/h4-6H2,1-3H3,(H,10,13)(H,11,12) checkY
    Key: SRPNQDXRVRCTNK-UHFFFAOYSA-N checkY
  • CC(C)(C)C(=O)NCCCC(O)=O
Properties
C9H17NO3
Molar mass 187.239 g·mol−1
Pharmacology
N06AX15 (WHO)
Oral
Pharmacokinetics:
6.4 hours
Legal status
  • In general: ℞ (Prescription only)
Related compounds
Related alkanoic acids
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Pivagabine (INN; brand name Tonerg), also known as N-pivaloyl-γ-aminobutyric acid or N-pivaloyl-GABA, is an antidepressant and anxiolytic drug which was introduced in Italy in 1997 for the treatment of depressive and maladaptive syndromes. But it was discontinued in Italy (according to Martindale). Originally believed to function as a prodrug to GABA, pivagabine is now believed to act somehow via modulation of corticotropin-releasing factor (CRF).

See also


Новое сообщение