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Proxibarbital
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Proxibarbital

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Proxibarbital
Proxibarbital.svg
Clinical data
Other names Proxibarbital, Centralgol, Ipronal, 5-Allyl-5-(β-hydroxypropyl)barbituric acid
ATC code
Identifiers
  • (RS)-5-allyl-5-(2-hydroxypropyl)pyrimidine-2,4,6(1H,3H,5H)-trione
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
ECHA InfoCard 100.018.004
Chemical and physical data
Formula C10H14N2O4
Molar mass 226.232 g·mol−1
3D model (JSmol)
  • O=C1NC(=O)NC(=O)C1(CC(O)C)C\C=C
  • InChI=1S/C10H14N2O4/c1-3-4-10(5-6(2)13)7(14)11-9(16)12-8(10)15/h3,6,13H,1,4-5H2,2H3,(H2,11,12,14,15,16) checkY
  • Key:VNLMRPAWAMPLNZ-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Proxibarbital (Ipronal) is a barbiturate derivative synthesized in 1956. It has anti-anxiety properties and is, in contrast to most barbiturates, almost without hypnotic action.

It was also used in the treatment of migraine headaches in a similar manner to butalbital.

Valofane isomerises to Proxibarbal in vivo.


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