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Prodrug
Triclofos
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Triclofos

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Triclofos
Triclofos-2D-skeletal.svg
Triclofos-3D-balls.png
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
  • 2,2,2-trichloroethanol dihydrogen phosphate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.005.624
Chemical and physical data
Formula C2H4Cl3O4P
Molar mass 229.37 g·mol−1
3D model (JSmol)
  • ClC(Cl)(Cl)COP(=O)(O)O
  • InChI=1S/C2H4Cl3O4P/c3-2(4,5)1-9-10(6,7)8/h1H2,(H2,6,7,8) checkY
  • Key:YYQRGCZGSFRBAM-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Triclofos is a sedative drug used rarely for treating insomnia.

Triclofos is a prodrug which is metabolised in the liver into the active drug trichloroethanol. The half-life of triclofos is fairly long and it may cause drowsiness the next day. Trichloroethanol may cause liver damage and triclofos should not be used for extended periods.

Triclofos is no longer available in the United States.

Side effects

Side effects may include: headache, rash, dizziness, flatulence, confusion, nightmares, dependence, diarrhoea, constipation, nausea, vomiting, abdominal pain, and ataxia.



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