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Prodrug
Tybamate
Другие языки:

Tybamate

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Tybamate
Tybamate.svg
Clinical data
ATC code
  • none
Identifiers
  • [2-(Carbamoyloxymethyl)-2-methylpentyl] N-butylcarbamate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard 100.022.050
Chemical and physical data
Formula C13H26N2O4
Molar mass 274.361 g·mol−1
3D model (JSmol)
  • CCCCNC(=O)OCC(C)(CCC)COC(=O)N
  • InChI=1S/C13H26N2O4/c1-4-6-8-15-12(17)19-10-13(3,7-5-2)9-18-11(14)16/h4-10H2,1-3H3,(H2,14,16)(H,15,17) ☒N
  • Key:PRBORDFJHHAISJ-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Tybamate (INN; Solacen, Tybatran, Effisax) is an anxiolytic of the carbamate family. It is a prodrug for meprobamate in the same way as the better known drug carisoprodol. It has liver enzyme inducing effects similar to those of phenobarbital but much weaker.

As the trade name Tybatran (Robins), it was formerly available in capsules of 125, 250, and 350 mg, taken 3 or 4 times a day for a total daily dosage of 750 mg to 2 g. The plasma half-life of the drug is three hours. At high doses in combination with phenothiazines, it could produce convulsions.




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