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Urofollitropin
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Urofollitropin

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Urofollitropin
Clinical data
Trade names Bravelle, Fertinex
AHFS/Drugs.com Micromedex Detailed Consumer Information
Routes of
administration
Subcutaneous, intramuscular
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
  • none
UNII
KEGG
ChEMBL
ECHA InfoCard 100.212.030
Chemical and physical data
Formula C975H1513N267O304S26
Molar mass 22672.95 g·mol−1
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Urofollitropin is a purified form of follicle-stimulating hormone (FSH) that is manufactured by extraction from human urine and then purified to remove various proteins and other substances. FSH is important in the development of follicles (eggs) produced by the ovaries. Given by subcutaneous injection, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility. It is also used with in vitro fertilization methods. The dosage is adjusted to each individual's response.

The most common side effects are abdominal or pelvic pain, bloating, as well as redness, pain or swelling at the injection site. Follitropin is possibly associated with increased risk of endometrial carcinoma. It is not for use during pregnancy, as there is evidence for birth defects under follitropin treatment.

Bravelle sold in the United States from March 2014 through October 2015 is subject to a recall and refund by its maker, Ferring Pharmaceuticals, because certain batches of the medicine had a lower strength than stated.

External links

  • Bravelle, by Ferring Pharmaceuticals, Switzerland
  • Fostimon by Institut Biochemique SA, Switzerland

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