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Zipeprol
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Zipeprol

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Zipeprol
Zipeprol.png
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral
ATC code
Legal status
Legal status
Identifiers
  • 1-methoxy- 3-[4-(2-methoxy- 2-phenylethyl)piperazin- 1-yl]- 1-phenylpropan- 2-ol
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard 100.047.432
Chemical and physical data
Formula C23H32N2O3
Molar mass 384.520 g·mol−1
3D model (JSmol)
  • OC(CN1CCN(CC1)CC(OC)c2ccccc2)C(OC)c3ccccc3
  • InChI=1S/C23H32N2O3/c1-27-22(19-9-5-3-6-10-19)18-25-15-13-24(14-16-25)17-21(26)23(28-2)20-11-7-4-8-12-20/h3-12,21-23,26H,13-18H2,1-2H3 checkY
  • Key:VSTNNAYSCJQCQI-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Zipeprol is a centrally acting cough suppressant developed in France in the 1970s. It is not a morphinan derivative (in contrast to codeine and dextromethorphan). Zipeprol acts as a local anaesthetic and has mucolytic, antihistamine and anticholinergic properties. It is sold with several brand names such as Zinolta and Respilene. It is not available in the United States or Canada and has been discontinued in Europe. It is still available in some countries in Asia and South America.

Zipeprol has been misused in Korea, mainly for the hallucinations it produces. Such use has become an issue due to the seizures and various neurological side effects it causes at high dosages.


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