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Aliskiren/amlodipine/hydrochlorothiazide
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Aliskiren/amlodipine/hydrochlorothiazide

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Aliskiren/amlodipine/hydrochlorothiazide
Combination of
Aliskiren Renin inhibitor
Amlodipine Calcium channel blocker
Hydrochlorothiazide Diuretic
Clinical data
Trade names Amturnide
AHFS/Drugs.com Micromedex Detailed Consumer Information
License data
Routes of
administration
By mouth
ATC code
Legal status
Legal status
Identifiers
PubChem CID
KEGG
Chemical and physical data
Formula C57H86Cl2N8O15S2
Molar mass 1258.38 g·mol−1
3D model (JSmol)
  • CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.CC(C)C(CC1=CC(=C(C=C1)OC)OCCCOC)CC(C(CC(C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
  • InChI=1S/C30H53N3O6.C20H25ClN2O5.C7H8ClN3O4S2/c1-19(2)22(14-21-10-11-26(38-8)27(15-21)39-13-9-12-37-7)16-24(31)25(34)17-23(20(3)4)28(35)33-18-30(5,6)29(32)36;1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h10-11,15,19-20,22-25,34H,9,12-14,16-18,31H2,1-8H3,(H2,32,36)(H,33,35);5-8,17,23H,4,9-11,22H2,1-3H3;1-2,10-11H,3H2,(H2,9,12,13)/t22-,23+,24-,25-;;/m0../s1
  • Key:YJDDFLDXUPNQTO-WMEHTASQSA-N
  (verify)

Aliskiren/amlodipine/hydrochlorothiazide, sold under the brand name Amturnide, is a fixed-dose combination medication that is used to treat high blood pressure. It contains aliskiren, amlodipine, and hydrochlorothiazide. It is taken by mouth.

It was approved for medical use in the United States in December 2010. Amturnide was withdrawn by Novartis from the US market in 2017.

External links



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