Chlormerodrin

Chlormerodrin

Names
IUPAC name 3-carbamoylamino-2-methoxypropylmercury(II) chloride
Systematic IUPAC name 3-chloro-mercura-2-methoxy propylurea
Other names Chloromeridin Chlormerodin Chlormerodrine Chlormeroprin Diurone Katonil Mercardox Mercloran Mercoral Merculest Merilid Neogidrin Neohydrin Oricur Percapyl Promeran Promerane 3-chloro-mercuri-2-methoxy propylurea [3-(Carbamoylamino)-2-methoxypropyl](chloro)mercury
Identifiers
CAS Number	62-37-3
3D model (JSmol)	Interactive image
ECHA InfoCard	100.000.483
PubChem CID	25210
SMILES COC(CNC(N)=O)C[Hg]Cl
Properties
Chemical formula	C5H11ClHgN2O2
Molar mass	367.20 g·mol−1
Appearance	Solid
Melting point	152.5 °C (306.5 °F; 425.6 K)
Solubility in water	11 g/l
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	Renal mercury poisoning
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Chlormerodrin

Clinical data
AHFS/Drugs.com	Medical Encyclopedia
ATC code	none
Legal status
Legal status	US: Withdrawn
Identifiers
IUPAC name 3-carbamoylamino-2-methoxypropylmercury(II) chloride
CAS Number	62-37-3
PubChem CID	25210
DrugBank	DB00534
ChemSpider	2615
UNII	99T5TWO621
ChEBI	CHEBI:59445
ChEMBL	ChEMBL2110562
ECHA InfoCard	100.000.483
Chemical and physical data
Formula	C5H11ClHgN2O2
Molar mass	367.196 g·mol−1
3D model (JSmol)	Interactive image
SMILES COC(CNC(=O)N)C[Hg]Cl
InChI InChI=1S/C5H11N2O2.ClH.Hg/c1-4(9-2)3-7-5(6)8;;/h4H,1,3H2,2H3,(H3,6,7,8);1H;/q;;+1/p-1 Key:BJFGVYCULWBXKF-UHFFFAOYSA-M

Chlormerodrin is a mercurial diuretic commercially traded from 1952 until 1974 that was once used to treat patients with heart failure, but is no longer in widespread use. The radiolabelled form (¹⁹⁷Hg & ²⁰³Hg) had also been used for medical imaging of the kidney and brain and the ¹⁹⁷Hg form was even considered a contender for ^99mTc by some physicians, but was ultimately discontinued by the FDA in 1989.