Buclizine

Buclizine

Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
ATC code	R06AE01 (WHO)
Identifiers
IUPAC name (RS)-1-[(4-chlorophenyl)- phenyl-methyl]-4- [(4-tert-butylphenyl) methyl] piperazine
CAS Number	82-95-1 Y
PubChem CID	6729
IUPHAR/BPS	7134
DrugBank	DB00354 Y
ChemSpider	6473 Y
UNII	0C94V6X681
ChEBI	CHEBI:3205 Y
ChEMBL	ChEMBL1201271 N
CompTox Dashboard (EPA)	DTXSID0022694
ECHA InfoCard	100.001.317
Chemical and physical data
Formula	C28H33ClN2
Molar mass	433.04 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES Clc1ccc(cc1)C(c2ccccc2)N3CCN(CC3)Cc4ccc(cc4)C(C)(C)C
InChI InChI=1S/C28H33ClN2/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24/h4-16,27H,17-21H2,1-3H3 Y Key:MOYGZHXDRJNJEP-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.

In the United Kingdom, buclizine is one of three drugs contained in Migraleve tablets, marketed by McNeil Healthcare for migraines.