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Abandoned drugs
Cloxestradiol
Другие языки:

    Cloxestradiol

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    Cloxestradiol
    Cloxestradiol.svg
    Clinical data
    Other names 17-(2,2,2-Trichloroethoxy)estradiol; 17-(1-Hydroxy-2,2,2-trichloroethoxy)estra-1,3,5(10-trien-3-ol
    Drug class Estrogen; Estrogen ether
    Identifiers
    • (8R,9S,13S,14S,17S)-13-methyl-17-(2,2,2-trichloro-1-hydroxyethoxy)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-ol
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    Chemical and physical data
    Formula C20H25Cl3O3
    Molar mass 419.77 g·mol−1
    3D model (JSmol)
    • C[C@]12CC[C@@H]3c4ccc(cc4CC[C@H]3[C@@H]1CC[C@@H]2OC(C(Cl)(Cl)Cl)O)O
    • InChI=1S/C20H25Cl3O3/c1-19-9-8-14-13-5-3-12(24)10-11(13)2-4-15(14)16(19)6-7-17(19)26-18(25)20(21,22)23/h3,5,10,14-18,24-25H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18?,19+/m1/s1
    • Key:JVLHMVXGPLKLFV-AJUWMHLFSA-N

    Cloxestradiol (INN), also known as 17-(2,2,2-trichloroethoxy)estradiol, is a synthetic, steroidal estrogen which was never marketed. It is an analogue of estradiol with a 2,2,2-trichloroethoxy substitution. The O,O-diacetate derivative, cloxestradiol acetate (brand name Genovul), has been marketed as an estrogen.

    See also




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