Dexbrompheniramine

Dexbrompheniramine

Clinical data
Trade names	Drixoril, Conex, Dixaphedrine
AHFS/Drugs.com	Multum Consumer Information
Routes of administration	Oral
ATC code	R06AB06 (WHO)
Legal status
Legal status	CA: OTC US: OTC
Pharmacokinetic data
Elimination half-life	25 hours
Identifiers
IUPAC name (3S)-3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine
CAS Number	132-21-8 Y
PubChem CID	16960
IUPHAR/BPS	7588
DrugBank	DB00405 Y
ChemSpider	16068 Y
UNII	75T64B71RP
ChEBI	CHEBI:59269 Y
ChEMBL	ChEMBL1201287 N
CompTox Dashboard (EPA)	DTXSID8022905
ECHA InfoCard	100.004.595
Chemical and physical data
Formula	C16H19BrN2
Molar mass	319.246 g·mol−1
3D model (JSmol)	Interactive image
SMILES Brc1ccc(cc1)[C@@H](c2ncccc2)CCN(C)C
InChI InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3/t15-/m0/s1 Y Key:ZDIGNSYAACHWNL-HNNXBMFYSA-N Y
NY (what is this?)  (verify)

Dexbrompheniramine is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active dextrorotatory isomer of brompheniramine. It was formerly marketed in combination with pseudoephedrine under the name Drixoral in the US and Canada. It is an alkylamine antihistamine.

Dexbrompheniramine is a first generation antihistamine that reduces the effects of the neurotransmitter histamine in the body; sneezing, itching, watery eyes, and runny nose.

Interactions

MAO inhibitors within 14 days. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Potassium

Drinking alcohol can increase side effects of dexbrompheniramine.

External links

• Media related to Dexbrompheniramine at Wikimedia Commons