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Isothipendyl

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Isothipendyl
Skeletal formula
Ball-and-stick model of isothipendyl
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Identifiers
  • N,N-dimethyl-1-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propan-2-amine
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard 100.006.890
Chemical and physical data
Formula C16H19N3S
Molar mass 285.41 g·mol−1
3D model (JSmol)
  • n2c1N(c3c(Sc1ccc2)cccc3)CC(N(C)C)C
  • InChI=1S/C16H19N3S/c1-12(18(2)3)11-19-13-7-4-5-8-14(13)20-15-9-6-10-17-16(15)19/h4-10,12H,11H2,1-3H3 checkY
  • Key:OQJBSDFFQWMKBQ-UHFFFAOYSA-N checkY
  (verify)

Isothipendyl is a 1st generation H1 antagonist (antihistamine) and anticholinergic used as an antipruritic. It is nowadays scarcely used in the 1st line relief of allergies due to the anticholinergic side effect of somnolence but does have some limited use through topical application in the relief of insect bites and related itching (pruritus).

See also


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