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Abandoned drugs
Lavoltidine
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Lavoltidine

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Lavoltidine
Lavoltidine.svg
Clinical data
Routes of
administration		 Oral
ATC code
  • none
Legal status
Legal status
  • Development terminated
Identifiers
  • [1-methyl-5-[3-[3-(piperidin-1-ylmethyl)phenoxy]propylamino]-1,2,4-triazol-3-yl]methanol
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C19H29N5O2
Molar mass 359.474 g·mol−1
3D model (JSmol)
  • OCc1nn(C)c(n1)NCCCOc2cccc(c2)CN3CCCCC3

Lavoltidine (INN,USAN, BAN; previously known as loxtidine, code name AH-23,844) is a highly potent and selective H2 receptor antagonist which was under development by Glaxo Wellcome (now GlaxoSmithKline) as a treatment for gastroesophageal reflux disease but was discontinued due to the discovery that it produced gastric carcinoid tumors in rodents.

See also


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