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Lodoxamide
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Lodoxamide

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Lodoxamide
Lodoxamide.svg
Names
Preferred IUPAC name
N,N′-(2-Chloro-5-cyano-1,3-phenylene)dioxamic acid
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
UNII
  • InChI=1S/C11H6ClN3O6/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21) ☒N
    Key: RVGLGHVJXCETIO-UHFFFAOYSA-N ☒N
  • InChI=1/C11H6ClN3O6/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21)
    Key: RVGLGHVJXCETIO-UHFFFAOYAZ
  • N#Cc1cc(NC(=O)C(=O)O)c(Cl)c(NC(=O)C(=O)O)c1
Properties
C11H6ClN3O6
Molar mass 311.63 g·mol−1
Pharmacology
S01GX05 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Lodoxamide is an antiallergic pharmaceutical drug. It is marketed under the tradename Alomide in the UK. Like cromoglicic acid it acts as a mast cell stabilizer. In 2014 lodoxamide and bufrolin were found to be potent agonists at the G protein-coupled receptor 35, an orphan receptor believed to play a role in inflammatory processes, pain and the development of stomach cancer.

See also



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