Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
Abandoned drugs
PD-217,014
Другие языки:

    PD-217,014

    Подписчиков: 0, рейтинг: 0
    PD-217,014
    PD-217,014.svg
    Identifiers
    • (1α,3α,5α)-3-aminomethyl-bicyclo[3.2.0]heptane-3-acetic acid
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    Chemical and physical data
    Formula C10H17NO2
    Molar mass 183.251 g·mol−1
    3D model (JSmol)
    • C1C[C@@H]2[C@H]1C[C@](C2)(CC(=O)O)CN
    • InChI=1S/C10H17NO2/c11-6-10(5-9(12)13)3-7-1-2-8(7)4-10/h7-8H,1-6,11H2,(H,12,13)/t7-,8+,10+
    • Key:NDDZVQRQVFTNSN-MBTKJCJQSA-N

    PD-217,014 is a drug developed by Pfizer and related to gabapentin, which similarly binds to the α2δ calcium channels (1 and 2). It was developed as a potentially more potent successor to gabapentin and pregabalin, along with several other analogues such as atagabalin and 4-methylpregabalin, but while PD-217,014 produces visceral analgesic effects in animal studies with higher potency and efficacy than gabapentin, it was not developed further for clinical use because of its comparatively more complex synthesis, compared to other related analogues.


    Новое сообщение