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Abandoned drugs
Pentagestrone
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    Pentagestrone

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    Pentagestrone
    Pentagestrone.svg
    Clinical data
    Other names 17α-Hydroxyprogesterone 3-cyclopentyl enol ether
    Drug class Progestogen ether
    Identifiers
    • 1-[(8R,9S,10R,13S,14S,17R)-3-cyclopentyloxy-17-hydroxy-10,13-dimethyl-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]ethanone
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    ChEMBL
    Chemical and physical data
    Formula C26H38O3
    Molar mass 398.587 g·mol−1
    3D model (JSmol)
    • CC(=O)C1(CCC2C1(CCC3C2CC=C4C3(CCC(=C4)OC5CCCC5)C)C)O
    • InChI=1S/C26H38O3/c1-17(27)26(28)15-12-23-21-9-8-18-16-20(29-19-6-4-5-7-19)10-13-24(18,2)22(21)11-14-25(23,26)3/h8,16,19,21-23,28H,4-7,9-15H2,1-3H3/t21-,22+,23+,24+,25+,26+/m1/s1
    • Key:RBFQPFFCDLXWQK-UXUCURBISA-N

    Pentagestrone (INN), also known as 17α-hydroxyprogesterone 3-cyclopentyl enol ether, is a steroidal progestin of the 17α-hydroxyprogesterone group that was never marketed. An acetate ester, pentagestrone acetate (Gestovis, Gestovister), has been marketed for clinical use. Pentagestrone was described in the literature in 1960.

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