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Pharmacology stubs
PHTPP
Другие языки:

    PHTPP

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    PHTPP
    PHTPP structure.svg
    Identifiers
    • 4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenol
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C20H11F6N3O
    Molar mass 423.318 g·mol−1
    3D model (JSmol)
    • C1=CC=C(C=C1)C2=NN3C(=CC(=NC3=C2C4=CC=C(C=C4)O)C(F)(F)F)C(F)(F)F
    • InChI=1S/C20H11F6N3O/c21-19(22,23)14-10-15(20(24,25)26)29-18(27-14)16(11-6-8-13(30)9-7-11)17(28-29)12-4-2-1-3-5-12/h1-10,30H
    • Key:AEZPAUSGTAHLOQ-UHFFFAOYSA-N

    PHTPP is a synthetic, nonsteroidal, and highly selective antagonist of ERβ that is used in scientific research to study the function of this receptor. It possesses 36-fold selectivity for ERβ over ERα, and is a silent antagonist of ERβ.

    See also


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