Pyrithyldione

Pyrithyldione

Clinical data
Trade names	Benedorm, Didropyridine, Dihydroprylone, Persedon, Presidon, Pyridion, Pyridione, Pyrithyldion, Pyrithyldione, Tetridin, Tetridine
ATC code	N05CE03 (WHO)
Identifiers
IUPAC name 3,3-diethylpyridine-2,4(1H,3H)-dione
CAS Number	77-04-3 N
PubChem CID	4994
ChemSpider	4820 Y
UNII	8AB20823CK
KEGG	D07329 Y
ChEMBL	ChEMBL1722501 N
CompTox Dashboard (EPA)	DTXSID4045262
ECHA InfoCard	100.000.910
Chemical and physical data
Formula	C9H13NO2
Molar mass	167.208 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C1N/C=C\C(=O)C1(CC)CC
InChI InChI=1S/C9H13NO2/c1-3-9(4-2)7(11)5-6-10-8(9)12/h5-6H,3-4H2,1-2H3,(H,10,12) Y Key:NZASCBIBXNPDMH-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Pyrithyldione (Presidon, Persedon) is a psychoactive drug invented in 1949. An improved method of manufacture was patented by Roche in 1959. It was used as a hypnotic or sedative and presumed to be less toxic than barbiturates. Today, this substance is no longer used. Agranulocytosis was sometimes reported as adverse effect. Pyrithyldione is also a CYP2D6 inducer but is not as potent as glutethimide In studies, it increased the O-Demethylation of codeine by 20%.

See also

• Methyprylon
• Piperidione
• Glutethimide