Pyrrolobenzodiazepines, (PBD) are a class of compound that may have antibiotic or anti-tumor properties.
Some dimeric pyrrolobenzodiazepines are used as the cytotoxic drug payloads in antibody-drug conjugates, for example in loncastuximab tesirine.
History
Anthramycin, the first PBD monomer, was first synthesized in the 1960s.