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Antiemetics
Ramosetron
Другие языки:

Ramosetron

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Ramosetron
Ramosetron.svg
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration		 By mouth (ODT), IV
ATC code
  • None
Pharmacokinetic data
Elimination half-life 5.8 hours
Identifiers
  • (1-Methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]methanone
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C17H17N3O
Molar mass 279.343 g·mol−1
3D model (JSmol)
  • CN1C=C(C2=CC=CC=C21)C(=O)[C@@H]3CCC4=C(C3)NC=N4
  • InChI=1S/C17H17N3O/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14/h2-5,9-11H,6-8H2,1H3,(H,18,19)/t11-/m1/s1 ☒N
  • Key:NTHPAPBPFQJABD-LLVKDONJSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Ramosetron (INN) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Ramosetron is also indicated for a treatment of "diarrhea-predominant irritable bowel syndrome in male and women". In India it is marketed under the brand name of Ibset.

It is only licensed for use in Japan and selected Southeast Asian countries. In Japan it is sold under the trade name Irribow. and in India as Ibset . 'Elsewhere it is commonly sold under the trade name Nasea and in India as Nozia (150 μg/mL injection & 100 μg oral tablet).


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