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Abandoned drugs
Ro48-8684
Другие языки:

Ro48-8684

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Ro48-8684
Ro48-8684.svg
Identifiers
  • 3-(5-dipropylaminomethyloxazol-2-yl)-8-fluoro-5-methyl-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepin-6-one
PubChem CID
ChemSpider
Chemical and physical data
Formula C22H26FN5O2
Molar mass 411.472 g·mol−1
3D model (JSmol)
  • CCCN(CC1=CN=C(C2=C(CN(C(C3=C4C=CC(F)=C3)=O)C)N4C=N2)O1)CCC
  • InChI=1S/C22H26FN5O2/c1-4-8-27(9-5-2)12-16-11-24-21(30-16)20-19-13-26(3)22(29)17-10-15(23)6-7-18(17)28(19)14-25-20/h6-7,10-11,14H,4-5,8-9,12-13H2,1-3H3
  • Key:YKKLHEHNUYCLQQ-UHFFFAOYSA-N
  (verify)

Ro48-8684 is a water-soluble benzodiazepine derivative developed by Hoffman-LaRoche in the 1990s, which was designed along with Ro48-6791 as an improved replacement for midazolam, but ultimately proved to have little advantages over the parent drug and has not been introduced into clinical practice.

See also



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