Talastine

Talastine

Clinical data
ATC code	R06AB07 (WHO)
Identifiers
IUPAC name 4-benzyl-2-[2-(dimethylamino)ethyl]phthalazin-1(2H)-one
CAS Number	16188-61-7 Y
PubChem CID	65624
ChemSpider	59065 Y
UNII	49AB2PA48B
CompTox Dashboard (EPA)	DTXSID20167265
Chemical and physical data
Formula	C19H21N3O
Molar mass	307.397 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C1c3ccccc3\C(=N/N1CCN(C)C)Cc2ccccc2
InChI InChI=1S/C19H21N3O/c1-21(2)12-13-22-19(23)17-11-7-6-10-16(17)18(20-22)14-15-8-4-3-5-9-15/h3-11H,12-14H2,1-2H3 Y Key:LCAAMXMULMCKLJ-UHFFFAOYSA-N Y
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Talastine (trade name Ahanon) is an antihistamine.

Synthesis

The amide proton from 4-Benzylphalazone is abstracted with KOH, which is then alkylated with diethylaminoethyl chloride.

External links

• "Talastine". Comparative Toxicogenomics Database.
• Talastine at the U.S. National Library of Medicine Medical Subject Headings (MeSH)