Tetrabamate (Atrium, G Tril, Sevrium) is a combination drug formulation of febarbamate, difebarbamate, and phenobarbital which was marketed in France and Spain and was used to treat anxiety and alcohol withdrawal-associated muscle tremors, agitation, and depression. It was largely, but not completely discontinued on April 4, 1997 after over 30 years of use due to reports of hepatitis and acute liver failure. The decision to restrict the use of the drug had been long-awaited.
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| Alcohols |
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| Barbiturates |
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| Benzodiazepines |
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| Carbamates |
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| Flavonoids |
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| Imidazoles |
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Kava constituents |
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| Monoureides |
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| Neuroactive steroids |
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| Nonbenzodiazepines |
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| Phenols |
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| Piperidinediones |
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| Pyrazolopyridines |
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| Quinazolinones |
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Volatiles/gases
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| Others/unsorted |
- 3-Hydroxybutanal
- α-EMTBL
- AA-29504
- Alogabat
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Avermectins (e.g., ivermectin)
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Bromide compounds (e.g., lithium bromide, potassium bromide, sodium bromide)
- Carbamazepine
- Chloralose
- Chlormezanone
- Clomethiazole
- Darigabat
- DEABL
- Deuterated etifoxine
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Dihydroergolines (e.g., dihydroergocryptine, dihydroergosine, dihydroergotamine, ergoloid (dihydroergotoxine))
- DS2
- Efavirenz
- Etazepine
- Etifoxine
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Fenamates (e.g., flufenamic acid, mefenamic acid, niflumic acid, tolfenamic acid)
- Fluoxetine
- Flupirtine
- Hopantenic acid
- KRM-II-81
- Lanthanum
- Lavender oil
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Lignans (e.g., 4-O-methylhonokiol, honokiol, magnolol, obovatol)
- Loreclezole
- Menthyl isovalerate (validolum)
- Monastrol
- Niacin
- Niacinamide
- Org 25,435
- Phenytoin
- Propanidid
- Retigabine (ezogabine)
- Safranal
- Seproxetine
- Stiripentol
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Sulfonylalkanes (e.g., sulfonmethane (sulfonal), tetronal, trional)
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Terpenoids (e.g., borneol)
- Topiramate
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Valerian constituents (e.g., isovaleric acid, isovaleramide, valerenic acid, valerenol)
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