Tosagestin

Tosagestin

Clinical data
Other names	ORG-30659; Exogestin; Letogestin; 11-Methylene-δ15-norethisterone; 17α-Ethynyl-11-methylene-19-nor-δ15-testosterone
Routes of administration	By mouth
Identifiers
IUPAC name (1S,2R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-15-methyl-17-methylidenetetracyclo[8.7.0.02,7.011,15]heptadeca-6,12-dien-5-one
CAS Number	110072-15-6
PubChem CID	159355
ChemSpider	140146
UNII	YS7Z529O22
KEGG	D06197
ChEMBL	ChEMBL2107658
CompTox Dashboard (EPA)	DTXSID50891344
Chemical and physical data
Formula	C21H24O2
Molar mass	308.421 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC12CC(=C)C3C(C1C=CC2(C#C)O)CCC4=CC(=O)CCC34
InChI InChI=1S/C21H24O2/c1-4-21(23)10-9-18-17-7-5-14-11-15(22)6-8-16(14)19(17)13(2)12-20(18,21)3/h1,9-11,16-19,23H,2,5-8,12H2,3H3/t16-,17-,18-,19+,20-,21-/m0/s1 Key:YJSTYQGZKJHXLN-OLGWUGKESA-N

Tosagestin (INN, USAN) (developmental code name ORG-30659), also known as 11-methylene-δ¹⁵-norethisterone or 17α-ethynyl-11-methylene-19-nor-δ¹⁵-testosterone, is a progestin of the 19-nortestosterone group which was under development by Organon in the United States and Europe as a hormonal contraceptive (in combination with ethinylestradiol) and for the treatment of menopausal symptoms but was never marketed.

See also

• Gestodene

External links

• Tosagestin - AdisInsight