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VUF-5681
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    VUF-5681

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    VUF-5681
    VUF-5681.svg
    Names
    Preferred IUPAC name
    4-[3-(1H-Imidazol-5-yl)propyl]piperidine
    Identifiers
    3D model (JSmol)
    ChemSpider
    PubChem CID
    • InChI=1S/C11H19N3/c1(3-11-8-13-9-14-11)2-10-4-6-12-7-5-10/h8-10,12H,1-7H2,(H,13,14) ☒N
      Key: YPGRNKJNOSUCLY-UHFFFAOYSA-N ☒N
    • InChI=1/C11H19N3/c1(3-11-8-13-9-14-11)2-10-4-6-12-7-5-10/h8-10,12H,1-7H2,(H,13,14)
      Key: YPGRNKJNOSUCLY-UHFFFAOYAZ
    • C1CNCCC1CCCC2=CN=CN2
    Properties
    C11H19N3
    Molar mass 193.288 g/mol
    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
    ☒N verify (what is checkY☒N ?)

    VUF-5681 is a potent and selective histamine antagonist which binds selectively to the H3 subtype. However while VUF-5681 blocks the activity of more potent H3 agonists, recent studies suggest that it may have some weak partial agonist activity when administered by itself.


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